Description

8(14)-Dehydro Norgestrel is a high-purity synthetic steroid intermediate, a key derivative in the norgestrel family. This compound is valued for its role as a critical building block in the synthesis of advanced pharmaceutical active ingredients. It is primarily required by research institutions and manufacturers in the pharmaceutical and life sciences sectors for the development and production of steroidal drugs and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of steroidal active pharmaceutical ingredients (APIs).
• Hormone Research: Used as a reference standard and starting material in biochemical and pharmacological research related to progestogens.
• Active Pharmaceutical Ingredient (API) Development: Serves as a key structural component in the R&D of new steroidal drug candidates.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of final drug substances.
• Analytical Standard: Employed in quality control laboratories for method development, validation, and as a high-purity calibration standard.

Basic Information

Product Name	8(14)-Dehydro Norgestrel
CAS No.	110785-09-6
Molecular Formula	C₂₁H₂₈O₂
Molecular Weight	312.45 g/mol
Synonyms	13-Ethyl-17-hydroxy-18,19-dinor-17α-pregna-4,8(14)-dien-20-yn-3-one; 8(14)-Dehydro-13β-ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one; δ8(14)-Norgestrel; 8,14-Dehydronorgestrel; 17α-Ethynyl-13β-ethyl-17β-hydroxy-4,8(14)-gonadien-3-one
EINECS	Contact for details

Quality Control

Our 8(14)-Dehydro Norgestrel is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards suitable for pharmaceutical R&D and synthesis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.