Description

3-Acetyl-n-[(Phenylmethoxy)Carbonyl]-L-Tyrosine Methyl Ester is a chemically modified, protected derivative of the amino acid L-Tyrosine. This compound is a critical building block (synthon) in advanced organic synthesis, particularly for the production of complex peptides and pharmaceutical intermediates. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Chemistry Research: Serves as a protected tyrosine derivative for solid-phase and solution-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptide sequences.
• Bioconjugation & Probe Development: Used in the creation of labeled peptides and biochemical probes for diagnostic and research applications.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the development of novel enzyme inhibitors or receptor ligands.
• Fine Chemical Synthesis: Acts as a chiral building block for the synthesis of non-peptide compounds requiring the specific stereochemistry and functional groups of tyrosine.

Basic Information

Product Name	3-Acetyl-n-[(Phenylmethoxy)Carbonyl]-L-Tyrosine Methyl Ester
CAS No.	110774-03-3
Molecular Formula	C20H21NO7
Molecular Weight	387.39 g/mol
Synonyms	N-Cbz-3-Acetyl-L-tyrosine methyl ester; Methyl N-[(benzyloxy)carbonyl]-3-acetyl-L-tyrosinate; Z-3-Acetyl-L-Tyrosine-OMe; (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-[4-(acetyloxy)phenyl]propanoic acid methyl ester; N-Carbobenzoxy-3-acetyl-L-tyrosine methyl ester; 3-Acetyl-N-Cbz-L-tyrosine methyl ester; Nα-Cbz-O-acetyl-L-tyrosine methyl ester; L-Tyrosine, N-[(phenylmethoxy)carbonyl]-, methyl ester, 3-acetate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with typical purity levels suitable for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles are available upon request. Our quality systems support development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.