Description

T-Butyl 4-Bromobutyrate is a valuable brominated ester building block used extensively in organic synthesis. Its primary importance lies in its role as a versatile alkylating agent and intermediate for constructing more complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and manufacturers in the fine chemical, pharmaceutical, and advanced material sectors who require high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a butyric acid derivative with a protected carboxylic acid group.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents where the 4-bromobutyl moiety is incorporated.
• Organic Synthesis Reagent: Serves as an alkylating agent in nucleophilic substitution reactions to introduce the 4-bromobutyl chain into target molecules.
• Polymer Chemistry: Acts as a monomer or chain transfer agent in the development of specialized polymers and functional materials.
• Liquid Crystal & Material Science: Intermediate in the synthesis of advanced organic materials, including liquid crystal compounds and organic electronic materials.
• Cross-Coupling Reactions: Suitable precursor for palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, after conversion to the corresponding boronic ester or other organometallic species.

Basic Information

Product Name	T-Butyl 4-Bromobutyrate
CAS No.	110661-91-1
Molecular Formula	C8H15BrO2
Molecular Weight	223.11 g/mol
Synonyms	tert-Butyl 4-bromobutanoate; 4-Bromobutanoic Acid tert-Butyl Ester; Butanoic acid, 4-bromo-, 1,1-dimethylethyl ester; 4-Bromobutyric Acid tert-Butyl Ester; tert-Butyl 4-bromobutanoate; t-Butyl 4-bromobutanoate; 1,1-Dimethylethyl 4-bromobutanoate
EINECS	Contact for details

Quality Control

Our T-Butyl 4-Bromobutyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or an opaque secondary container.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.4580 - 1.4620
Density	1.25 - 1.35 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.