Description

2-Oxa-3-Azabicyclo[2.2.2]Octane-3-Carboxylic Acid, Methyl Ester is a specialized bicyclic heterocyclic compound that serves as a valuable synthetic intermediate and building block in advanced organic chemistry. Its rigid, bridged structure makes it a key precursor for constructing complex molecular architectures, particularly in pharmaceutical research and fine chemical synthesis. This high-purity compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those requiring constrained, bridged ring systems to modulate biological activity and pharmacokinetic properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its unique heterocyclic scaffold can impart specific modes of action.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Science: Can be incorporated as a monomer or cross-linking agent to create polymers with specific thermal or mechanical properties.
• Academic & R&D: Employed in university and institutional research for methodological studies in heterocyclic and synthetic organic chemistry.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	2-Oxa-3-Azabicyclo[2.2.2]Octane-3-Carboxylic Acid, Methyl Ester
CAS No.	110589-97-4
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	Methyl 2-oxa-3-azabicyclo[2.2.2]octane-3-carboxylate; 3-Carbomethoxy-2-oxa-3-azabicyclo[2.2.2]octane; 2-Oxa-3-azabicyclo[2.2.2]octane-3-carboxylic acid methyl ester; Bicyclo[2.2.2]octane, 2-oxa-3-aza-3-carbomethoxy-; Methyl 3-azabicyclo[2.2.2]octane-3-carboxylate 2-oxide (related); 3-Methoxycarbonyl-2-oxa-3-azabicyclo[2.2.2]octane
EINECS	Contact for details

Quality Control

Our 2-Oxa-3-Azabicyclo[2.2.2]Octane-3-Carboxylic Acid, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.