Description

Methyl 2,3,5-Tri-o-Acetylpentofuranoside is a key protected carbohydrate intermediate, specifically a fully acetylated methyl furanoside derivative. This compound is essential for synthetic chemists as it provides a versatile, reactive scaffold for the controlled synthesis of complex nucleosides, nucleotides, and other bioactive sugar-modified molecules. It is primarily utilized in pharmaceutical research and development, serving as a critical building block for antiviral and anticancer drug candidates, as well as in advanced material science applications.

Application

• Nucleoside/Nucleotide Synthesis: A crucial protected intermediate for the stepwise construction of modified nucleosides used in antiviral (e.g., HCV, HIV) and anticancer therapies.
• Pharmaceutical Intermediates: Serves as a key starting material or advanced intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry Research: Used in academic and industrial R&D for studying glycosylation reactions, protecting group strategies, and synthesizing complex oligosaccharides.
• Prodrug Development: The acetyl protecting groups can be utilized in the design of prodrugs to enhance the bioavailability and stability of therapeutic agents.
• Material Science: Potential monomer or precursor for synthesizing specialized polymers and functional materials with tailored properties.

Basic Information

Product Name	Methyl 2,3,5-Tri-o-Acetylpentofuranoside
CAS No.	110415-63-9
Molecular Formula	C12H18O8
Molecular Weight	290.26 g/mol
Synonyms	Methyl 2,3,5-Tri-O-acetylpentofuranoside; Methyl Triacetylpentofuranoside; 1-O-Methyl-2,3,5-tri-O-acetyl-pentofuranose; Pentofuranoside, methyl, triacetate; Methyl 2,3,5-Triacetylpentofuranoside; Acetylated Methyl Pentofuranoside
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our high-purity chemical intermediates. Each batch of Methyl 2,3,5-Tri-o-Acetylpentofuranoside is analyzed using advanced techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.