Description

T-Butyl2-Iodobenzoate is a high-purity, specialized organic intermediate featuring a sterically hindered tert-butyl ester group and an iodine substituent on the aromatic ring. This unique molecular architecture makes it a valuable building block for advanced synthesis in pharmaceutical and agrochemical research, where precise structural control is critical. It is primarily utilized by R&D chemists and process development scientists for constructing complex molecules, particularly in cross-coupling reactions and as a precursor for functionalized benzoic acid derivatives.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), especially in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators requiring halogenated aromatic cores.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and material science.
• Organic Electronic Materials: A potential building block for research into organic semiconductors and light-emitting materials due to its halogenated aromatic structure.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new synthetic pathways in organic chemistry.
• Fine Chemical Production: Integral in the multi-step synthesis of complex, high-value fine chemicals and specialty additives.

Basic Information

Product Name	T-Butyl2-Iodobenzoate
CAS No.	110349-26-3
Molecular Formula	C11H13IO2
Molecular Weight	304.13 g/mol
Synonyms	2-Iodobenzoic Acid tert-Butyl Ester; tert-Butyl 2-Iodobenzoate; Benzoic acid, 2-iodo-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 2-iodobenzoate; T-Butyl O-Iodobenzoate; 2-Iodo-benzoic acid tert-butyl ester; TBD-Iodobenzoate
EINECS	Contact for details

Quality Control

Every batch of T-Butyl2-Iodobenzoate is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is supplied with each shipment to guarantee compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.