Description

Ethyl 2-Iodosylbenzoate is a specialized hypervalent iodine(III) reagent, a key compound in modern synthetic organic chemistry. Its primary value lies in its powerful oxidizing properties and its role as a versatile electrophile for constructing carbon-heteroatom and carbon-carbon bonds under mild conditions. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, enabling innovative synthetic routes and process optimization.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for the oxidative functionalization of complex molecules, including the synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development and scale-up of novel pesticides and herbicides through selective oxidation reactions.
• Organic Methodology Development: Serves as a key electrophilic reagent in academic and industrial R&D for discovering new C–O, C–N, and C–C bond-forming reactions.
• Material Science Precursor: Employed in the synthesis of specialized monomers and polymers requiring controlled oxidative coupling steps.
• Catalyst and Ligand Modification: Useful for the oxidative modification of catalyst frameworks to tune their activity and selectivity.

Basic Information

Product Name	Ethyl 2-Iodosylbenzoate
CAS No.	110349-23-0
Molecular Formula	C9H9IO3
Molecular Weight	292.07 g/mol
Synonyms	Ethyl o-Iodosobenzoate; 2-(Ethoxycarbonyl)iodosylbenzene; o-Iodosobenzoic Acid Ethyl Ester; (Ethoxycarbonyl)(oxo)-λ3-iodanylbenzene; IBX Ethyl Ester; 1-Ethoxy-1,2-benziodoxol-3(1H)-one; Ethyl 1-Hydroxy-1,2-benziodoxol-3(1H)-one 1-Oxide
EINECS	Contact for details

Quality Control

Our Ethyl 2-Iodosylbenzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality protocols are designed to meet the stringent requirements of our global customer base in fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term stability to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.