Description

3-Oxo-3-(3-Trifluoromethylphenyl)Propionic Acid Ethyl Ester is a high-value fluorinated organic intermediate with a versatile β-ketoester structure. This compound is critical for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors for constructing trifluoromethyl-substituted aromatic frameworks.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) containing the trifluoromethylphenyl moiety, which is known to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group contributes to efficacy and environmental persistence profiles.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated monomers and polymers for specialty coatings, electronics, and high-performance materials.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags to study biological systems and enzyme mechanisms.

Basic Information

Product Name	3-Oxo-3-(3-Trifluoromethylphenyl)Propionic Acid Ethyl Ester
CAS No.	110193-60-7
Molecular Formula	C12H11F3O3
Molecular Weight	260.21 g/mol
Synonyms	Ethyl 3-oxo-3-[3-(trifluoromethyl)phenyl]propanoate; Ethyl 3-oxo-3-(3-trifluoromethylphenyl)propionate; 3-(3-Trifluoromethylphenyl)-3-oxopropionic Acid Ethyl Ester; 3-Oxo-3-(m-trifluoromethylphenyl)propionic Acid Ethyl Ester; β-Keto Ester of 3-Trifluoromethylbenzoic Acid; Ethyl (3-Trifluoromethylbenzoyl)acetate; 110193-60-7; m-Trifluoromethylbenzoylacetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our production of 3-Oxo-3-(3-Trifluoromethylphenyl)Propionic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity for critical synthetic applications. All material is characterized by advanced analytical techniques including HPLC, GC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment. We operate under a quality system aligned with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.