Description

tert-Butyl 4-Nitrobutanoate is a valuable nitro ester building block in organic synthesis. This compound matters for its role as a protected intermediate, enabling the controlled introduction of the 4-nitrobutanoate moiety into more complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Key synthetic intermediate in the preparation of pharmaceutical candidates, particularly those containing γ-aminobutyric acid (GABA) analogues.
• Building block for the synthesis of complex natural products and bioactive molecules requiring a protected carboxylic acid functionality.
• Precursor in medicinal chemistry for constructing molecules with nitroalkane segments that can be further reduced to amines.
• Used in process chemistry for scaling up the production of target compounds where the tert-butyl ester group offers advantageous stability and deprotection profiles.
• Starting material in agrochemical research for developing new active ingredients.
• Versatile reagent in academic and industrial R&D laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	tert-Butyl 4-Nitrobutanoate
CAS No.	110106-95-1
Molecular Formula	C8H15NO4
Molecular Weight	189.21 g/mol
Synonyms	4-Nitrobutyric Acid tert-Butyl Ester; Butanoic acid, 4-nitro-, 1,1-dimethylethyl ester; tert-Butyl 4-nitrobutyrate; 1,1-Dimethylethyl 4-nitrobutanoate; 4-Nitrobutanoic Acid tert-Butyl Ester; t-Butyl 4-nitrobutanoate; tert-Butyl ester of 4-nitrobutanoic acid
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Nitrobutanoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere such as nitrogen or argon for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.