Description

Methyl Difluoroiodoacetate is a versatile fluorinated building block and a key reagent in advanced organic synthesis. Its value lies in its ability to introduce both fluorine and iodine functional groups, enabling the construction of complex molecules with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require specialized intermediates for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A critical reagent for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, pesticides, and fungicides with enhanced properties.
• Fluorinated Building Block: Serves as a key precursor for introducing difluoroacetate and iodoacetate motifs into complex organic frameworks.
• Material Science Research: Employed in the creation of specialty polymers and advanced materials with unique surface characteristics.
• Cross-Coupling Reactions: Acts as an electrophile in palladium-catalyzed cross-coupling reactions (e.g., Negishi, Stille) to form carbon-carbon bonds.
• Radical Chemistry: A useful substrate for radical-mediated transformations, facilitating the synthesis of complex fluorinated structures.

Basic Information

Product Name	Methyl Difluoroiodoacetate
CAS No.	109872-87-9
Molecular Formula	C3H3F2IO2
Molecular Weight	235.96 g/mol
Synonyms	Methyl 2,2-difluoro-2-iodoacetate; Iododifluoroacetic Acid Methyl Ester; Methyl Iododifluoroacetate; Difluoro(iodo)acetic Acid Methyl Ester; Methyl 2-iodo-2,2-difluoroacetate; Acetic acid, 2,2-difluoro-2-iodo-, methyl ester; Methyl α,α-difluoro-α-iodoacetate
EINECS	Contact for details

Quality Control

Our Methyl Difluoroiodoacetate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, NMR, and FTIR for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactivity, it is recommended to handle under an inert atmosphere for extended storage and use appropriate chemical storage cabinets.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.