Description

Arteether is a potent semi-synthetic artemisinin derivative, a key active pharmaceutical ingredient (API) in the global fight against malaria. Its primary value lies in its efficacy against severe and multidrug-resistant strains of *Plasmodium falciparum*, offering a critical therapeutic option. This compound is essential for pharmaceutical manufacturers and research institutions developing injectable antimalarial formulations. Its stability profile and mechanism of action make it a cornerstone in modern antimalarial chemotherapy.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable formulations for the treatment of severe and complicated malaria.
• Combination Therapy: Used in the development of Artemisinin-based Combination Therapies (ACTs) to combat drug resistance.
• Veterinary Medicine: Research and development of antiprotozoal treatments for veterinary applications.
• Biomedical Research: A critical reference standard and tool compound for parasitology, pharmacology, and drug resistance studies.
• Drug Discovery: Serves as a lead compound for synthesizing novel analogs with improved pharmacokinetic properties.

Basic Information

Product Name	Arteether
CAS No.	109716-83-8
Molecular Formula	C17H28O5
Molecular Weight	312.40 g/mol
Synonyms	Artemotil; Dihydroartemisinin Ethyl Ether; β-Arteether; Arteether (USP); SM-242; RP-56426; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
EINECS	Contact for details

Quality Control

Our Arteether is manufactured under strict quality management systems, targeting compliance with USP/Pharmaceutical grade standards. Every batch undergoes comprehensive analytical testing including identity confirmation, purity assay, and impurity profiling to ensure it meets stringent specifications for pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) to prevent oxidation, at a controlled room temperature of 15-25°C. The container must be kept in a cool, dry, and well-ventilated area, away from sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.