Description

Cyclopropanecarboxylic Acid, 2-(Hydroxymethyl)-, Ethyl Ester, (1S-Trans)- (9Ci) is a high-purity, chiral cyclopropane derivative that serves as a critical building block in advanced organic synthesis. Its unique stereochemistry and functional group arrangement make it a valuable intermediate for constructing complex molecular architectures with high enantiomeric purity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and antiviral applications.
• Asymmetric Synthesis: Utilized as a precursor in catalytic asymmetric reactions to introduce the cyclopropane moiety with high stereocontrol.
• Agrochemical Research: Serves as a building block for the synthesis of advanced, biologically active compounds in crop protection research.
• Material Science: Investigated for the synthesis of specialized monomers and polymers with unique structural properties.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(Hydroxymethyl)-, Ethyl Ester, (1S-Trans)- (9Ci)
CAS No.	109716-55-4
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(1S,2S)-2-(Hydroxymethyl)cyclopropanecarboxylic acid ethyl ester; Ethyl (1S,2S)-2-(hydroxymethyl)cyclopropanecarboxylate; trans-(1S,2S)-2-(Hydroxymethyl)cyclopropanecarboxylic acid ethyl ester; (1S-trans)-2-(Hydroxymethyl)cyclopropanecarboxylic Acid Ethyl Ester; (1S,2S)-2-Hydroxymethylcyclopropanecarboxylic acid ethyl ester; (1S,2S)-Ethyl 2-(hydroxymethyl)cyclopropanecarboxylate; Chiral cyclopropane ester intermediate
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-(Hydroxymethyl)-, Ethyl Ester, (1S-Trans)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.