Description

(2S)-2-({[(1,1-Dimethylethyl)O×Y]Carbonyl}Amino)-3-Phenylpropyl Methanesulfonate is a chiral, non-natural amino acid derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block and intermediate for the development of complex, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly in the fields of peptide mimetics and protease inhibitors.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Peptidomimetics: Used to construct non-peptide scaffolds that mimic the structure and function of natural peptides for drug discovery.
• Protease Inhibitor Synthesis: Serves as a precursor in the synthesis of compounds designed to inhibit specific protease enzymes.
• Chemical Biology Research: Employed as a tool molecule for studying enzyme-substrate interactions and signal transduction pathways.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in stereoselective chemical reactions to introduce chiral centers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	(2S)-2-({[(1,1-Dimethylethyl)O×Y]Carbonyl}Amino)-3-Phenylpropyl Methanesulfonate
CAS No.	109687-66-3
Molecular Formula	C16H25NO5S
Molecular Weight	343.44 g/mol
Synonyms	N-[(1S)-2-(Methylsulfonyloxy)-1-benzylethyl]carbamic Acid 1,1-Dimethylethyl Ester; Boc-Phenylalaninol Mesylate; (2S)-2-({[(1,1-Dimethylethyl)oxy]carbonyl}amino)-3-phenylpropyl methanesulfonate; tert-Butyl N-[(1S)-2-(methylsulfonyloxy)-1-phenylethyl]carbamate; Boc-L-Phenylalaninol Methanesulfonate Ester; Boc-Phe-ol-OMs; (S)-tert-Butyl (1-(hydroxymethyl)-2-phenylethyl)carbamate methanesulfonate; N-Boc-L-phenylalaninol mesylate
EINECS	Contact for details

Quality Control

Our (2S)-2-({[(1,1-Dimethylethyl)O×Y]Carbonyl}Amino)-3-Phenylpropyl Methanesulfonate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.