Description

Fmoc-Ala-Odhbt CAS NO 109636-25-1 is a specialized amino acid derivative, specifically an Fmoc-protected alanine pre-activated with the ODHbt ester group. This compound is a critical building block in modern solid-phase peptide synthesis (SPPS), designed to enhance coupling efficiency and minimize racemization. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of complex peptides, peptidomimetics, and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a pre-activated ester for the efficient and high-yield incorporation of alanine residues into peptide chains.
• Pharmaceutical Research & Development: For the synthesis of peptide-based drug candidates, APIs (Active Pharmaceutical Ingredients), and diagnostic agents.
• Combinatorial Chemistry: Used in the generation of peptide libraries for high-throughput screening and drug discovery programs.
• Bioconjugation: Serving as a reagent for the site-specific labeling or modification of proteins and other biomolecules.
• Academic Research: A key reagent in biochemistry and organic chemistry laboratories for studying peptide structure, function, and synthesis methodologies.
• Production of Custom Peptides: By CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) offering bespoke peptide synthesis services.

Basic Information

Product Name	Fmoc-Ala-Odhbt
CAS No.	109636-25-1
Molecular Formula	C26H22N4O6
Molecular Weight	486.48 g/mol
Synonyms	Fmoc-L-Alanine 3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl Ester; Fmoc-Ala-OBt; 9-Fluorenylmethyloxycarbonyl-L-alanine 3-hydroxy-1,2,3-benzotriazin-4(3H)-one ester; Fmoc-Alanine Benzotriazolyl Ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine 3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl ester; Fmoc-Ala-OBzt; Fmoc-Alanine ODHBt Ester; Fmoc-Ala-O(1H-1,2,3-benzotriazin-4(3H)-one-3-yl)
EINECS	Contact for details

Quality Control

Our Fmoc-Ala-Odhbt is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and performance. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.