Description

2-Cyano-3-Pyridin-3-Yl-Thioacrylamide is a specialized organic intermediate featuring a unique cyano-thioacrylamide scaffold attached to a pyridine ring. This molecular structure makes it a valuable building block for the synthesis of complex heterocyclic compounds and functional materials. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and advanced material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways where the pyridine-thioamide motif is active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its reactive cyano and thioamide groups for creating bioactive molecules.
• Ligand Synthesis: Acts as a starting material for creating chelating ligands in coordination chemistry and catalysis.
• Material Science: Employed in the research of organic semiconductors, conductive polymers, or metal-organic frameworks (MOFs) due to its electron-withdrawing and coordinating properties.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function or protein interactions.

Basic Information

Product Name	2-Cyano-3-Pyridin-3-Yl-Thioacrylamide
CAS No.	109628-96-8
Molecular Formula	C9H7N3S
Molecular Weight	189.24 g/mol
Synonyms	3-Pyridinyl 2-cyano-3-(thioxomethyl)-2-propenamide; 2-Cyano-3-(3-pyridinylthio)acrylamide; (2Z)-2-Cyano-3-(pyridin-3-ylsulfanyl)prop-2-enamide; 3-Pyridinyl 2-cyano-3-mercapto-2-propenoate; Thioacrylamide derivative, 2-cyano-3-(3-pyridinylthio)-; NSC 339586
EINECS	Contact for details

Quality Control

Our 2-Cyano-3-Pyridin-3-Yl-Thioacrylamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.