Description

3-[[(1,1-Dimethyl)Dimethylsily]Oxy]Pentanedioic Acid Monomethyl Ester is a high-value organosilicon-protected glutaric acid derivative, serving as a critical protected intermediate in complex organic synthesis. Its primary value lies in enabling selective chemical transformations, particularly in the synthesis of pharmaceuticals and advanced fine chemicals where precise control over carboxylic acid functionality is required. This compound is essential for R&D chemists and production specialists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to streamline multi-step synthetic routes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing glutaric acid or succinic acid motifs.
• Peptide Synthesis: Used as a protected dicarboxylic acid component in the preparation of peptide analogs and mimetics.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated chelating ligands for metal catalysis and coordination chemistry.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Used in surface modification and the creation of silicon-containing hybrid organic-inorganic materials.

Basic Information

Product Name	3-[[(1,1-Dimethyl)Dimethylsily]Oxy]Pentanedioic Acid Monomethyl Ester
CAS No.	109462-20-6
Molecular Formula	C11H22O5Si
Molecular Weight	262.38 g/mol
Synonyms	Monomethyl 3-[(tert-butyldimethylsilyl)oxy]glutarate; 3-[(tert-Butyldimethylsilyl)oxy]pentanedioic acid monomethyl ester; 3-(TBDMSO)glutaric acid monomethyl ester; Methyl 3-((tert-butyldimethylsilyl)oxy)glutarate; Glutaric acid, 3-[(1,1-dimethylethyl)dimethylsilyl]oxy]-, monomethyl ester; 3-O-(tert-Butyldimethylsilyl)glutaric acid monomethyl ester; TBDMS-protected glutaric acid monomethyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity synthetic intermediates. Every batch is characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) are available upon request, detailing all relevant specifications to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can compromise product integrity. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.