Description

2-Methoxyisobutyl Isocyanide is a specialized organic building block featuring both an isocyanide and an ether functional group. This unique bifunctional structure makes it a valuable reagent in modern synthetic chemistry, particularly for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for constructing heterocyclic cores common in medicinal chemistry.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides and herbicides, leveraging its reactivity to create complex bioactive molecules.
• Multicomponent Reactions (MCRs): An essential component in Passerini and Ugi-type reactions for the efficient, one-pot generation of diverse compound libraries for high-throughput screening.
• Ligand Synthesis: Serves as a building block for the preparation of specialized isocyanide-based ligands used in catalysis and material science.
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and foldamers with potential therapeutic applications.
• Chemical Biology Probes: Useful for creating activity-based probes and other tools to study biological processes and enzyme functions.

Basic Information

Item	Detail
Product Name	2-Methoxyisobutyl Isocyanide
CAS No.	109434-22-2
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	1-Isocyano-2-methoxy-2-methylpropane; 2-Methoxy-2-methylpropyl isocyanide; (2-Methoxy-2-methylpropyl)isocyanide; 2-Methoxyisobutylisonitrile; Isobutyl, 2-methoxy-, isocyanide; 2-Methoxy-2-methyl-1-isocyanopropane
EINECS	Contact for details

Quality Control

Our 2-Methoxyisobutyl Isocyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flame. Due to the reactive nature of isocyanides, containers should be kept tightly sealed under an inert atmosphere when not in use to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.