Description

2-p-Tolylthiazolo[5,4-b]pyridine is a specialized heterocyclic organic compound featuring a fused thiazole and pyridine ring system substituted with a p-tolyl group. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Serves as a core structure for developing new pesticides and herbicides with potential enhanced efficacy and selectivity.
• Organic Light-Emitting Diodes (OLEDs): Used as a building block for electron-transport materials or host materials in OLED displays and lighting due to its rigid, conjugated structure.
• Ligand in Catalysis: Can be functionalized to create novel ligands for transition metal catalysts used in cross-coupling and other synthetic transformations.
• Material Science: Investigated for the development of organic semiconductors and other advanced functional materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	2-p-Tolylthiazolo[5,4-b]pyridine
CAS No.	109202-20-2
Molecular Formula	C15H12N2S
Molecular Weight	252.33 g/mol
Synonyms	2-(4-Methylphenyl)thiazolo[5,4-b]pyridine; 2-(p-Tolyl)thiazolo[5,4-b]pyridine; 2-(4-Methylphenyl)[1,3]thiazolo[5,4-b]pyridine; Thiazolo[5,4-b]pyridine, 2-(4-methylphenyl)-; 2-(4-Tolyl)thiazolo[5,4-b]pyridine
EINECS	Contact for details

Quality Control

Our production of 2-p-Tolylthiazolo[5,4-b]pyridine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to support cGMP requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.