Description

4-(Bis(2-Chloroethyl)Amino)-5-Methoxy-2-Nitrobenzofuran is a specialized heterocyclic compound featuring a benzofuran core functionalized with a nitrogen mustard moiety. This molecular structure makes it a valuable intermediate in advanced organic synthesis, particularly for the development of targeted bioactive molecules. It is primarily sought by research institutions and pharmaceutical development companies engaged in the creation of novel therapeutic agents and chemical probes.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of potential anticancer agents and other biologically active nitrogen mustard derivatives.
• Chemical Biology Research: Used as a precursor for developing molecular probes to study enzyme inhibition and DNA alkylation mechanisms.
• Advanced Organic Synthesis: Serves as a versatile intermediate for constructing complex heterocyclic frameworks in medicinal chemistry programs.
• Life Science Reagents: Utilized in the preparation of specialized reagents for biochemical and pharmacological screening assays.

Basic Information

Product Name	4-(Bis(2-Chloroethyl)Amino)-5-Methoxy-2-Nitrobenzofuran
CAS No.	109143-19-3
Molecular Formula	C15H16Cl2N2O4
Molecular Weight	359.21 g/mol
Synonyms	5-Methoxy-2-nitro-4-[bis(2-chloroethyl)amino]benzofuran; 4-[Bis(2-chloroethyl)amino]-5-methoxy-2-nitrobenzofuran; 2-Nitro-4-[bis(2-chloroethyl)amino]-5-methoxybenzofuran; Benzofuran, 4-[bis(2-chloroethyl)amino]-5-methoxy-2-nitro-; 109143-19-3
EINECS	Contact for details

Quality Control

Every batch of 4-(Bis(2-Chloroethyl)Amino)-5-Methoxy-2-Nitrobenzofuran is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for research and development purposes. A detailed Certificate of Analysis (COA) with specifications for purity (typically by HPLC), identity confirmation (IR, NMR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.