Description

6-(Bis(2-Chloroethyl)Amino)-2-Nitrobenzofuran is a specialized heterocyclic compound featuring a benzofuran core functionalized with a nitrogen mustard group and a nitro substituent. This unique structure makes it a valuable intermediate for the synthesis of more complex molecules in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis. The compound's reactivity profile offers a strategic building block for constructing targeted bioactive agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of novel therapeutic agents, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in drug discovery programs, leveraging its nitrogen mustard moiety for alkylation studies.
• Bioconjugate Development: Potential use in the synthesis of antibody-drug conjugates (ADCs) or other targeted delivery systems due to its reactive chloroethyl groups.
• Agrochemical Synthesis: Acts as an intermediate in the development of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the design of molecular probes to study biological processes and protein interactions.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	6-(Bis(2-Chloroethyl)Amino)-2-Nitrobenzofuran
CAS No.	109143-17-1
Molecular Formula	C₁₄H₁₄Cl₂N₂O₃
Molecular Weight	329.18 g/mol
Synonyms	6-[Bis(2-chloroethyl)amino]-2-nitrobenzofuran; 2-Nitro-6-(bis(2-chloroethyl)amino)benzofuran; 6-(Bis(2-chloroethyl)amino)-2-nitro-1-benzofuran; 6-(N,N-Bis(2-chloroethyl)amino)-2-nitrobenzofuran; Benzofuran, 6-[bis(2-chloroethyl)amino]-2-nitro-; 109143-17-1; 6-(Di(2-chloroethyl)amino)-2-nitrobenzofuran
EINECS	Contact for details

Quality Control

Our production of 6-(Bis(2-Chloroethyl)Amino)-2-Nitrobenzofuran adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.