Description

5-(Bis(2-Chloroethyl)Amino)-2-Nitrobenzofuran is a specialized organic compound featuring a benzofuran core functionalized with a nitrogen mustard group and a nitro substituent. This unique molecular architecture makes it a valuable intermediate for the synthesis of more complex bioactive molecules, particularly in pharmaceutical research and development. It is primarily sought by chemical manufacturers and R&D laboratories engaged in the creation of novel therapeutic agents and advanced material science applications.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of potential anticancer agents, leveraging its nitrogen mustard moiety.
• Chemical Research: Used as a precursor for developing novel heterocyclic compounds and studying structure-activity relationships (SAR).
• Bioconjugation Studies: Employed in the development of targeted drug delivery systems and antibody-drug conjugates (ADCs).
• Material Science: Serves as a monomer or functionalizing agent in the synthesis of specialized polymers and advanced organic materials.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents with specific biological activity.

Basic Information

Product Name	5-(Bis(2-Chloroethyl)Amino)-2-Nitrobenzofuran
CAS No.	109143-16-0
Molecular Formula	C₁₄H₁₄Cl₂N₂O₃
Molecular Weight	329.18 g/mol
Synonyms	5-[Bis(2-chloroethyl)amino]-2-nitrobenzofuran; 2-Nitro-5-[bis(2-chloroethyl)amino]benzofuran; 5-(N,N-Bis(2-chloroethyl)amino)-2-nitrobenzofuran; NSC 382080; Benzofuran, 5-[bis(2-chloroethyl)amino]-2-nitro-
EINECS	Contact for details

Quality Control

Our 5-(Bis(2-Chloroethyl)Amino)-2-Nitrobenzofuran is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.