Description

(E)-1,3-Bis(4-Hydroxyphenyl)Prop-2-En-1-One is a high-purity diarylpropenone derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a conjugated enone system flanked by phenolic groups, makes it a versatile intermediate for creating complex molecules with specific electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, including potential anti-inflammatory, anticancer, and neuroprotective agents.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, leveraging its structural motif for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced organic electronic materials.
• UV Absorber & Stabilizer Precursor: A foundational compound for synthesizing organic molecules designed to absorb ultraviolet light for use in coatings and plastics.
• Chemical Biology Probe Development: Utilized in creating molecular probes to study biological pathways and protein interactions due to its modifiable phenolic and ketone functionalities.
• Fine Chemical Synthesis: Intermediate for producing complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	(E)-1,3-Bis(4-Hydroxyphenyl)Prop-2-En-1-One
CAS No.	108997-30-4
Molecular Formula	C₁₅H₁₂O₃
Molecular Weight	240.26 g/mol
Synonyms	(E)-1,3-Bis(4-hydroxyphenyl)-2-propen-1-one; 3,4'-Dihydroxychalcone; 4,4'-Dihydroxychalcone; NSC 407296; Bis(4-hydroxyphenyl)propenone; Chalcone, 4,4'-dihydroxy-; (E)-3-(4-Hydroxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
EINECS	Contact for details

Quality Control

Our (E)-1,3-Bis(4-Hydroxyphenyl)Prop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	215 - 220 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.