Description

Silane, [[(1α,3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-Triene-1,3-Diyl]Bis(Oxy)]Bis[(1,1-Dimethylethyl)Dimethyl- is a high-purity, organosilicon-modified derivative of a secocholestatriene structure, designed for advanced research and synthesis. This compound is valued for its unique molecular architecture, which combines the reactivity of a silane with the complex steroidal backbone, making it a critical intermediate in pharmaceutical development and specialized organic synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel active compounds and materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel vitamin D analogs and other steroidal therapeutic agents.
• Advanced Material Science: Used in the development of functionalized surfaces and hybrid organic-inorganic materials due to its silane group.
• Chemical Research: Serves as a specialized reagent in organic synthesis for introducing the secocholestatriene moiety into target molecules.
• Bioconjugation: Potential use in creating steroid-protein conjugates for diagnostic or targeted drug delivery applications.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Silane, [[(1α,3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-Triene-1,3-Diyl]Bis(Oxy)]Bis[(1,1-Dimethylethyl)Dimethyl-
CAS No.	108887-35-0
Molecular Formula	C39H68O2Si2
Molecular Weight	625.1 g/mol
Synonyms	tert-Butyldimethyl[[[(1α,3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3-diyl]bis(oxy)]bis[tert-butyldimethylsilyl]] Ether; 1,3-Bis-O-(tert-butyldimethylsilyl)-9,10-secocholesta-5,7,10(19)-triene; TBDMS Ether of 1,3-Dihydroxy-9,10-secocholesta-5,7,10(19)-triene; Silylated Vitamin D Intermediate; 1α,3β-Bis(tert-butyldimethylsilyloxy)-9,10-secocholesta-5,7,10(19)-triene
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the primary container to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.