Description

Neurodye Rh-461 is a specialized fluorescent dye compound used as a vital tool in advanced neuroscience and biomedical research. Its core value lies in its ability to act as a sensitive probe for neuronal activity and cellular imaging, providing critical data on physiological processes. This product is essential for researchers and manufacturers in the fields of neurobiology, diagnostic assay development, and high-throughput screening technologies.

Application

• Neuronal Activity Imaging: Used as a fluorescent indicator for monitoring electrical activity and calcium dynamics in neurons and neural networks.
• Biomedical Research: Serves as a key reagent in fluorescence microscopy and confocal imaging for studying cellular physiology and signal transduction.
• Diagnostic Assay Development: Employed in the formulation of research-use-only (RUO) kits and assays for detecting specific biological targets.
• High-Throughput Screening (HTS): Utilized in drug discovery platforms to identify compounds that modulate ion channels or neuronal function.
• Sensor Technology: A component in the development of optical chemical sensors and biosensors for analytical applications.

Basic Information

Product Name	Neurodye Rh-461
CAS No.	108641-88-9
Molecular Formula	C29H31N3O3
Molecular Weight	469.58 g/mol
Synonyms	RH-461; Neuro Dye RH-461; Rhodol derivative RH-461; 2-(6-(Diethylamino)-3-(diethyliminio)-3H-xanthen-9-yl)-5-(dimethylamino)benzoate; Fluorescent voltage-sensitive dye RH-461; Neuronal potentiometric dye.
EINECS	Contact for details

Quality Control

Our Neurodye Rh-461 is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance characteristics. We adhere to relevant standards for research chemicals, ensuring reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is strictly light-sensitive and hygroscopic (moisture-sensitive). For long-term stability, consider storage under desiccated conditions or an inert atmosphere.

Specification

Item	Specification
Appearance	Dark red to purple solid or powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Fluorescence Properties	Conforms to reference (Ex/Em maxima)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.