Description

D-Proline, 4-Amino-5-Oxo-, Ethyl Ester, (4S)-Rel- (9Ci) CAS NO 108636-54-0 is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry at the 4-position. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecules with precise stereocontrol. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide mimetics, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential active pharmaceutical ingredients (APIs), particularly in protease inhibitor research.
• Peptidomimetic Chemistry: Used to introduce constrained proline analogs into peptide backbones to enhance metabolic stability and biological activity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand in catalytic asymmetric reactions to induce enantioselectivity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to amino acid metabolism and processing.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex, high-value specialty chemicals and agrochemicals.
• Academic Research: Utilized in methodological development and total synthesis projects within university and institutional laboratories.

Basic Information

Product Name	D-Proline, 4-Amino-5-Oxo-, Ethyl Ester, (4S)-Rel- (9Ci)
CAS No.	108636-54-0
Molecular Formula	C7H12N2O3
Molecular Weight	172.18 g/mol
Synonyms	(4S)-4-Amino-5-oxo-D-proline ethyl ester; Ethyl (4S)-4-amino-5-oxo-D-prolinate; Ethyl 4-amino-5-oxo-D-prolinate; 4-Amino-5-oxo-D-proline ethyl ester; D-4-Amino-5-oxoproline ethyl ester; (S)-Ethyl 4-amino-5-oxopyrrolidine-2-carboxylate; 108636-54-0; (4S)-rel-4-Amino-5-oxo-D-proline ethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our D-Proline, 4-Amino-5-Oxo-, Ethyl Ester, (4S)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.