Description

(3S)-3,4-Dihydroxybutanoic Acid Ethyl Ester is a chiral synthon of significant value in fine chemical and pharmaceutical synthesis. Its bifunctional diol and ester groups make it a versatile building block for constructing complex molecular architectures. This compound is particularly sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of statin drugs (e.g., Rosuvastatin, Atorvastatin) and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Building Block: Employed in asymmetric synthesis for creating complex natural products and specialty chemicals.
• Biochemical Research: Serves as a substrate or intermediate in enzymatic studies and metabolic pathway research.
• Polymer Chemistry: Acts as a monomer or co-monomer for synthesizing functionalized, biodegradable polyesters.
• Ligand and Catalyst Development: Utilized in the preparation of chiral ligands for asymmetric catalysis.

Basic Information

Product Name	(3S)-3,4-Dihydroxybutanoic Acid Ethyl Ester
CAS No.	108585-47-3
Molecular Formula	C6H12O4
Molecular Weight	148.16 g/mol
Synonyms	(S)-Ethyl 3,4-dihydroxybutanoate; (3S)-3,4-Dihydroxybutyric Acid Ethyl Ester; Ethyl (S)-3,4-Dihydroxybutyrate; L-Ethyl 3,4-Dihydroxybutyrate; (S)-3,4-Dihydroxybutanoic Acid Ethyl Ester; Ethyl L-3,4-Dihydroxybutyrate; (S)-(-)-Ethyl 3,4-dihydroxybutyrate
EINECS	Contact for details

Quality Control

Our (3S)-3,4-Dihydroxybutanoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.