Description

7-Coumaryl Triflate is a specialized chemical intermediate, a trifluoromethanesulfonate ester derivative of 7-hydroxycoumarin. This compound is valued for its role as a versatile building block in organic synthesis, particularly in cross-coupling reactions and the preparation of more complex coumarin derivatives. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel coumarin-based drug candidates with potential biological activity.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the coumarin scaffold is integral.
• Organic Synthesis Reagent: Acts as an effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the reactivity of the triflate leaving group.
• Fluorescent Probe & Dye Precursor: Serves as a starting material for synthesizing advanced fluorescent tags and laser dyes based on the coumarin core structure.
• Material Science: Employed in creating organic electronic materials and photoactive polymers.
• Academic & R&D Laboratories: A crucial reagent for methodological studies and exploring new synthetic pathways in university and corporate research settings.

Basic Information

Product Name	7-Coumaryl Triflate
CAS No.	108530-10-5
Molecular Formula	C10H5F3O5S
Molecular Weight	294.21 g/mol
Synonyms	7-Hydroxycoumarin Triflate; 7-Hydroxy-2H-chromen-2-one Trifluoromethanesulfonate; 7-Coumarinol Triflate; 7-(Trifluoromethanesulfonyloxy)-2H-chromen-2-one; 7-Triflyloxycoumarin; Umbelliferone Triflate; 7-OTf Coumarin
EINECS	Contact for details

Quality Control

Our 7-Coumaryl Triflate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. The product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability. Keep container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.