Description

4-Chloro-3-Methoxyphenylisocyanate is a versatile aromatic isocyanate building block used in the synthesis of advanced chemical intermediates. Its value lies in its high reactivity, which enables the efficient introduction of the isocyanate functional group into target molecules for further derivatization. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of urea and carbamate-based drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where it serves as a precursor for ureas and other bioactive compounds.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the production of specialty polyurethanes, coatings, and adhesives with tailored properties.
• Chemical Research: Essential reagent in organic synthesis for constructing heterocycles and other complex molecular architectures via reactions with amines and alcohols.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of specialized colorants and functional dyes.

Basic Information

Product Name	4-Chloro-3-Methoxyphenylisocyanate
CAS No.	108438-11-5
Molecular Formula	C8H6ClNO2
Molecular Weight	183.59 g/mol
Synonyms	1-Chloro-4-isocyanato-2-methoxybenzene; 4-Chloro-3-methoxybenzenisocyanate; 3-Methoxy-4-chlorophenyl isocyanate; 2-Methoxy-5-chlorophenyl isocyanate; Isocyanic acid, 4-chloro-3-methoxyphenyl ester; (4-Chloro-3-methoxyphenyl)isocyanate
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Methoxyphenylisocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, containers must be kept tightly sealed under a dry inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.