Description

tert-Butyl 3-oxopropionate is a versatile and high-purity chemical intermediate, primarily valued for its role as a key building block in advanced organic synthesis. Its reactive β-keto ester functionality makes it an essential precursor for constructing complex molecular architectures, offering chemists a reliable and efficient pathway. This compound is particularly critical for research and production in the pharmaceutical and agrochemical sectors, where it is used to develop active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing β-keto ester or pyrazole moieties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its reactivity to form heterocyclic structures.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty chemicals requiring controlled ester and ketone functionalities.
• Academic & Industrial R&D: A valuable reagent in process chemistry and medicinal chemistry research for developing new synthetic methodologies and novel compounds.
• Polymer Chemistry: Can be utilized as a monomer or co-monomer in the synthesis of specialized polymers with tailored properties.
• Cross-Coupling Reactions: Acts as a substrate in various metal-catalyzed coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	tert-Butyl 3-Oxopropionate
CAS No.	108350-21-6
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	3-Oxobutanoic acid tert-butyl ester; tert-Butyl acetoacetate; tert-Butyl 3-oxobutanoate; 3-Oxobutyric acid tert-butyl ester; Butanoic acid, 3-oxo-, 1,1-dimethylethyl ester; Acetoacetic acid tert-butyl ester; t-Butyl acetoacetate; BAA
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-oxopropionate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chromatography and spectroscopy, to confirm identity and meet stringent impurity profiles. Certificates of Analysis (COA) documenting purity, assay, and specific tests are available for every shipment upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material may be moisture-sensitive; ensure containers are kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.