Description

1,2,3,4-Tetra-o-Acetyl-6-Diphenylphosphoryl-β-D-Mannopyranose is a key, high-purity synthetic intermediate in carbohydrate and medicinal chemistry. Its value lies in its role as a versatile building block for the stereoselective synthesis of complex oligosaccharides, glycoconjugates, and nucleoside analogues. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing novel therapeutics, diagnostic tools, and advanced biomaterials.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of antiviral and anticancer nucleoside drugs.
• Glycobiology Research: Used in the chemical and enzymatic synthesis of complex, biologically active oligosaccharides and glycoproteins.
• Carbohydrate Chemistry: Serves as a key mannose donor with a participating protecting group for stereocontrolled glycosylation reactions.
• Probe & Diagnostic Development: Utilized in creating labeled sugars and glycoconjugates for imaging and diagnostic assays.
• Process Development: Employed in scaling up routes to carbohydrate-based active pharmaceutical ingredients (APIs).
• Academic & Industrial R&D: Fundamental reagent for exploring new synthetic methodologies and glycosylation mechanisms.

Basic Information

Product Name	1,2,3,4-Tetra-o-Acetyl-6-Diphenylphosphoryl-β-D-Mannopyranose
CAS No.	108321-48-8
Molecular Formula	C26H29O11P
Molecular Weight	548.48 g/mol
Synonyms	6-O-(Diphenylphosphoryl)-1,2,3,4-tetra-O-acetyl-β-D-mannopyranose; 1,2,3,4-Tetra-O-acetyl-6-O-(diphenylphosphoryl)-β-D-mannopyranose; β-D-Mannopyranose, 1,2,3,4-tetraacetate 6-(diphenyl phosphate); 6-Diphenylphosphoryl-1,2,3,4-tetra-O-acetyl-β-D-mannopyranose; Mannose-6-phosphate derivative (acetylated, diphenylphosphoryl); Ac4Man-OP(O)(OPh)2 (common abbreviation)
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetra-o-Acetyl-6-Diphenylphosphoryl-β-D-Mannopyranose is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR (1H, 13C, 31P), and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); containers should be sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent hydrolysis. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.