Description

Azidoalanine,tert-Butylester CAS NO 108283-47-2 is a specialized, protected amino acid derivative featuring an azido functional group. This compound is a critical building block in organic synthesis, particularly for the site-specific incorporation of chemical handles via click chemistry. It is primarily utilized by research scientists and process chemists in the pharmaceutical, biotechnology, and chemical research sectors for developing novel therapeutics and advanced materials.

Application

• Peptide Synthesis & Modification: Acts as a key intermediate for introducing azide groups into peptide backbones for subsequent bioconjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Chemical Biology Probes: Used in the synthesis of activity-based probes and photoaffinity labels to study protein function and interactions.
• Pharmaceutical Intermediate: Serves as a protected precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation & Linker Chemistry: Enables the covalent attachment of drugs, dyes, or other molecules to antibodies, proteins, or nanoparticles for targeted delivery and diagnostics.
• Material Science: Employed in the development of functionalized polymers and surfaces with specific bio-recognition properties.
• Academic & Industrial Research: A valuable reagent for methodological development in synthetic organic chemistry and bioorthogonal chemistry.

Basic Information

Product Name	Azidoalanine,tert-Butylester
CAS No.	108283-47-2
Molecular Formula	C7H13N3O2
Molecular Weight	171.20 g/mol
Synonyms	tert-Butyl 2-azido-3-aminopropanoate; 2-Azidoalanine tert-butyl ester; 3-Amino-2-azidopropanoic acid tert-butyl ester; N3-Azido-L-alanine tert-butyl ester; (2R)-2-Azido-3-aminopropanoic acid tert-butyl ester; L-Azidoalanine tert-butyl ester; Boc-Azidoalanine-OtBu (common abbreviation); Azido-Ala-OtBu
EINECS	Contact for details

Quality Control

Our Azidoalanine,tert-Butylester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical: 97-99%)
Specific Rotation	Contact for details
Water Content (KF)	<0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.