Description

Diethyl(Troc-Amino)Bromomethylphosphonate is a specialized organophosphorus compound with a bromomethyl and a Troc-protected amino group, making it a versatile building block in synthetic organic chemistry. Its primary value lies in its bifunctional reactivity, serving as a key intermediate for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This product is essential for research chemists and process development scientists engaged in constructing phosphonate esters, amino acid derivatives, and other bioactive compounds requiring selective protection and functionalization strategies.

Application

• Key phosphonate intermediate in the synthesis of novel pharmaceutical actives, including protease inhibitors and antiviral agents.
• Building block for constructing modified amino acids and peptides in medicinal chemistry research.
• Precursor in the development of agrochemicals, such as herbicides and plant growth regulators with phosphonate backbones.
• Reagent for the Horner-Wadsworth-Emmons (HWE) olefination reaction to form carbon-carbon double bonds.
• Intermediate in material science for the synthesis of functionalized polymers and ligands for catalysis.
• Used in academic and industrial R&D for exploring new synthetic methodologies and organophosphorus chemistry.

Basic Information

Product Name	Diethyl(Troc-Amino)Bromomethylphosphonate
CAS No.	108217-08-9
Molecular Formula	C9H17BrNO5P
Molecular Weight	330.11 g/mol
Synonyms	Diethyl [(2,2,2-Trichloroethoxycarbonyl)amino](bromomethyl)phosphonate; (Bromomethyl)[(2,2,2-Trichloroethoxy)carbonylamino]phosphonic Acid Diethyl Ester; TrocNHCH2P(O)(OEt)2Br; Diethyl (Troc-Amino)(bromomethyl)phosphonate; Phosphonic acid, [(2,2,2-trichloroethoxy)carbonylamino]bromomethyl-, diethyl ester; Bromomethyl-Troc-Amino-diethylphosphonate
EINECS	Contact for details

Quality Control

Our Diethyl(Troc-Amino)Bromomethylphosphonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP standards for advanced intermediate production where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.