Description

(4S,5R)-4-Formyl-2,2,5-Trimethyl-3-Oxazolidinecarboxylic Acid 1,1-Dimethylethyl Ester CAS NO 108149-62-8 is a high-purity, chiral oxazolidine derivative that serves as a critical advanced pharmaceutical intermediate and building block in organic synthesis. Its value lies in its defined stereochemistry and reactive formyl group, enabling the precise construction of complex molecules for active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and manufacturers in the pharmaceutical and fine chemical industries who require reliable, high-quality intermediates for the synthesis of chiral drugs and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of complex Active Pharmaceutical Ingredients (APIs), particularly for antibiotics and other therapeutic agents.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in stereoselective organic reactions to introduce specific stereocenters.
• Peptidomimetics Research: Serves as a constrained scaffold in the design and development of peptide-like molecules for drug discovery.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and probes for studying biological mechanisms and target identification.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for commercial pharmaceutical manufacturing.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(4S,5R)-4-Formyl-2,2,5-Trimethyl-3-Oxazolidinecarboxylic Acid 1,1-Dimethylethyl Ester
CAS No.	108149-62-8
Molecular Formula	C12H21NO4
Molecular Weight	243.30 g/mol
Synonyms	tert-Butyl (4S,5R)-4-formyl-2,2,5-trimethyl-1,3-oxazolidine-3-carboxylate; (4S,5R)-4-Formyl-2,2,5-trimethyl-3-oxazolidinecarboxylic acid tert-butyl ester; Boc-D-Ala-Thr(OBzl)-OH; (S,R)-4-Formyl-2,2,5-trimethyl-3-oxazolidinecarboxylic acid 1,1-dimethylethyl ester; Oxazolidine derivative 108149-62-8; Chiral oxazolidine aldehyde ester
EINECS	Contact for details

Quality Control

Our (4S,5R)-4-Formyl-2,2,5-Trimethyl-3-Oxazolidinecarboxylic Acid 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be sensitive to moisture; ensure the container is kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.