Description

1-(4-Hydroxyphenyl)-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One CAS NO 108132-05-4 is a high-purity synthetic chalcone derivative, a key chemical intermediate prized for its unique molecular scaffold. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the development of novel compounds with targeted biological activities. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the development of potential therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and metabolic disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological potency and selectivity.
• Biochemical Reagent: Employed in biochemical assays and as a reference standard for studying enzyme inhibition and cellular signaling pathways.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to construct more elaborate heterocyclic or polyfunctional molecules.
• Academic & Industrial R&D: Fundamental material for exploratory research in universities and corporate R&D labs focusing on new chemical entities.

Basic Information

Item	Details
Product Name	1-(4-Hydroxyphenyl)-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One
CAS No.	108132-05-4
Molecular Formula	C18H18O5
Molecular Weight	314.33 g/mol
Synonyms	3,4,5-Trimethoxychalcone-4'-ol; 4'-Hydroxy-3,4,5-trimethoxychalcone; 1-(4-Hydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one; (E)-1-(4-Hydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one; NSC 407296; Chalcone derivative 108132-05-4; Trimethoxyhydroxychalcone
EINECS	Contact for details

Quality Control

Our 1-(4-Hydroxyphenyl)-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.