Description

Pyridine, 4-(Chlorodimethylsilyl)-3-Fluoro- (9Ci) is a specialized organosilicon building block that combines a pyridine ring with reactive chlorosilane and fluorine substituents. This compound is valued for its dual functionality, serving as a key precursor in the synthesis of advanced silicon-containing materials and as a versatile ligand or intermediate in organometallic chemistry. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring silicon-based bioisosteres or fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Serves as a key building block for creating new-generation pesticides and herbicides, where the silicon and fluorine atoms contribute to enhanced activity and environmental persistence.
• Material Science Precursor: Employed in the development of functionalized silanes for surface modification, adhesion promoters, and as a monomer for specialty silicon-based polymers and resins.
• Ligand in Catalysis: Acts as a ligand for transition metal catalysts in cross-coupling and hydrosilylation reactions, leveraging the pyridine nitrogen for metal coordination.
• Organic Electronics: Utilized in the research and development of organic semiconductors and light-emitting materials due to its electron-deficient pyridine core and functional handles for further derivatization.
• Chemical Research (R&D): A valuable reagent for academic and industrial research in synthetic methodology development and the exploration of new organosilicon chemistry.

Basic Information

Product Name	Pyridine, 4-(Chlorodimethylsilyl)-3-Fluoro- (9Ci)
CAS No.	108093-98-7
Molecular Formula	C7H9ClFNSi
Molecular Weight	189.69 g/mol
Synonyms	3-Fluoro-4-(chlorodimethylsilyl)pyridine; 4-(Chlorodimethylsilyl)-3-fluoropyridine; (3-Fluoropyridin-4-yl)dimethylchlorosilane; Dimethyl(3-fluoro-4-pyridinyl)chlorosilane; 108093-98-7; 3-Fluoro-4-pyridinyldimethylchlorosilane; 4-Pyridinyl, 3-fluoro-, dimethylchlorosilane derivative
EINECS	Contact for details

Quality Control

Our production of Pyridine, 4-(Chlorodimethylsilyl)-3-Fluoro- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong acids and bases. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and air. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.