Description

Cyclopropanecarboxylic Acid, 2-(Hydroxymethyl)-1-Methyl-, Methyl Ester, trans- is a specialized chiral cyclopropane derivative that serves as a critical building block in advanced organic synthesis. Its unique sterically constrained structure and functional groups make it a valuable intermediate for constructing complex molecules with high stereochemical purity. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors. Its application is essential for the synthesis of novel active ingredients requiring precise three-dimensional architecture.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane ring contributes to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Employed in the synthesis of monomers or additives for specialized polymers with unique thermal or mechanical properties.
• Fine Chemical Production: Intermediate for manufacturing complex fragrance and flavor compounds that require specific stereochemistry.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(Hydroxymethyl)-1-Methyl-, Methyl Ester, trans-
CAS No.	107805-14-1
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	trans-2-(Hydroxymethyl)-1-methylcyclopropanecarboxylic acid methyl ester; Methyl trans-2-(hydroxymethyl)-1-methylcyclopropanecarboxylate; (1R,2S)-rel-2-(Hydroxymethyl)-1-methylcyclopropanecarboxylic Acid Methyl Ester; (1S,2R)-rel-2-(Hydroxymethyl)-1-methylcyclopropanecarboxylic Acid Methyl Ester; trans-1-Methyl-2-(hydroxymethyl)cyclopropanecarboxylic Acid Methyl Ester; Cyclopropanecarboxylic acid, 2-(hydroxymethyl)-1-methyl-, methyl ester, (1R,2S)-rel-; Cyclopropanecarboxylic acid, 2-(hydroxymethyl)-1-methyl-, methyl ester, (1S,2R)-rel-
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-(Hydroxymethyl)-1-Methyl-, Methyl Ester, trans- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request, providing full traceability and compliance documentation for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The compound is light-sensitive and should be stored away from light. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.