Description

Methyl 2-((Trimethylsilyl)Ethynyl)Benzoate CAS NO 107793-07-7 is a specialized organosilicon building block featuring a silyl-protected alkyne and a benzoate ester functional group. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, particularly in cross-coupling and cycloaddition reactions. It is primarily used by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring alkyne or aromatic ester functionalities.
• Agrochemical Synthesis: Used in the research and development of novel crop protection agents and herbicides.
• Material Science: Serves as a precursor in the development of organic semiconductors, liquid crystals, and other functional polymers.
• Organic Synthesis: A versatile reagent for Sonogashira coupling, click chemistry, and other metal-catalyzed transformations to create complex organic molecules.
• Chemical Research: Employed in academic and industrial R&D laboratories for method development and exploring new synthetic pathways.
• Fine Chemical Production: Used in the multi-step synthesis of specialty and performance chemicals.

Basic Information

Product Name	Methyl 2-((Trimethylsilyl)Ethynyl)Benzoate
CAS No.	107793-07-7
Molecular Formula	C13H16O2Si
Molecular Weight	232.35 g/mol
Synonyms	Methyl 2-[(trimethylsilyl)ethynyl]benzoate; 2-[(Trimethylsilyl)ethynyl]benzoic Acid Methyl Ester; Benzoic acid, 2-[(trimethylsilyl)ethynyl]-, methyl ester; Methyl o-((trimethylsilyl)ethynyl)benzoate; Methyl 2-(trimethylsilylethynyl)benzoate; TMS-Ethynyl Benzoate Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 2-((Trimethylsilyl)Ethynyl)Benzoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for all shipments. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.