Description

tert-Butyl 6-Methylnicotinate is a high-purity chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in the pharmaceutical sector. This compound is primarily needed by research institutions and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing nicotinic acid or pyridine-based pharmacophores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyridine moiety is a common structural feature.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for electronics and material science applications.
• Academic and R&D: Utilized in university and corporate research laboratories for method development and exploratory synthesis projects.
• Custom Synthesis Building Block: Provides a protected carboxylic acid group, making it a valuable substrate for multi-step custom synthesis contracts.

Basic Information

Product Name	tert-Butyl 6-Methylnicotinate
CAS No.	107756-09-2
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	6-Methylnicotinic acid tert-butyl ester; tert-Butyl 6-methylpyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 6-methyl-, 1,1-dimethylethyl ester; 6-Methyl-nicotinic acid tert-butyl ester; 1,1-Dimethylethyl 6-methyl-3-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Methylnicotinate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.