Description

Methyl 2-[Benzenesulfonylimino]-3,3,3-Trifluoropropionate CAS NO 107651-35-4 is a specialized fluorinated building block featuring a reactive N-sulfonyl imino ester moiety. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research and development chemists and process scale-up teams for constructing novel trifluoromethyl-containing heterocycles and active ingredients.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of active pharmaceutical ingredients (APIs) containing the biologically relevant trifluoromethyl group.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the CF3 group enhances metabolic stability and lipophilicity.
• Material Science Research: Serves as a precursor for novel fluorinated polymers or specialty chemicals with unique surface properties.
• Organic Synthesis Building Block: Employed in [3+2] cycloadditions and other reactions to construct nitrogen-containing heterocycles like pyrroles and pyrazoles.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes for studying enzyme mechanisms or binding interactions.

Basic Information

Product Name	Methyl 2-[Benzenesulfonylimino]-3,3,3-Trifluoropropionate
CAS No.	107651-35-4
Molecular Formula	C10H8F3NO4S
Molecular Weight	295.24 g/mol
Synonyms	Methyl 2-(Benzenesulfonylimino)-3,3,3-trifluoropropanoate; Methyl 3,3,3-Trifluoro-2-[(phenylsulfonyl)imino]propionate; 2-(Benzenesulfonylimino)-3,3,3-trifluoropropionic Acid Methyl Ester; N-(Phenylsulfonyl)trifluoropyruvate Methyl Ester Imine; Methyl (Z)-2-[(Benzenesulfonyl)imino]-3,3,3-trifluoropropanoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-[Benzenesulfonylimino]-3,3,3-Trifluoropropionate adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is characterized by modern analytical techniques, including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.