Description

(1S, 2S, 5R)-Neomenthyl Azide is a high-purity, chiral azide derivative of neomenthol, serving as a critical chiral building block and ligand precursor in advanced organic synthesis. Its defined stereochemistry and reactive azide functionality make it invaluable for introducing the neomenthyl moiety into complex molecular architectures via click chemistry and other azide-alkyne cycloaddition reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for the development of active ingredients and functional materials.

Application

• Chiral Auxiliary and Ligand Synthesis: Used as a precursor for chiral phosphines, amines, and other ligands crucial in asymmetric catalysis.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and investigational new drugs.
• Agrochemical Research: Employed in creating chiral analogs of pesticides and herbicides to study structure-activity relationships and improve efficacy.
• Click Chemistry Substrate: The azide group participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation, polymer functionalization, and material science.
• Organic Synthesis Reagent: Utilized in stereoselective synthesis to construct complex natural products and novel organic compounds with defined three-dimensional structures.
• Material Science: Acts as a monomer or cross-linker for developing advanced polymers with specific chiral or functional properties.

Basic Information

Product Name	(1S, 2S, 5R)-Neomenthyl Azide
CAS No.	107535-12-6
Molecular Formula	C₁₀H₁₉N₃
Molecular Weight	181.28 g/mol
Synonyms	(1S,2S,5R)-2-Isopropyl-5-methylcyclohexyl Azide; (-)-Neomenthyl Azide; (1S,2S,5R)-Neomenthyl Azide; Azidoneomenthol; 2-Isopropyl-5-methylcyclohexyl Azide (1S,2S,5R)-; Neomenthyl Azide
EINECS	Contact for details

Quality Control

Every batch of (1S, 2S, 5R)-Neomenthyl Azide is produced and tested under strict quality management systems to ensure exceptional purity and stereochemical integrity. Our standard grade meets high-purity specifications suitable for research and development, with Certificates of Analysis (COA) provided for each shipment, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. We adhere to cGMP principles where applicable, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and highly volatile nature, containers must be kept sealed and away from heat and ignition sources. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Density	~0.95 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.