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3-Hydroxy-13,17-Seco-5-Androsten-17-Oic-13,17-Lactam (4-(Bis(2-Chloroethyl)Amino)Phenyl)Butyrate CAS NO 107480-21-7


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CAS No.:107480-21-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Hydroxy-13,17-Seco-5-Androsten-17-Oic-13,17-Lactam (4-(Bis(2-Chloroethyl)Amino)Phenyl)Butyrate is a chemically modified steroid derivative with a nitrogen mustard moiety, designed for targeted biological activity. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the exploration of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies specializing in oncology and endocrinology for the synthesis of potential prodrugs and targeted cytostatic compounds.

Application

  • Pharmaceutical Intermediate: Key building block in the research and synthesis of novel steroid-based therapeutic agents.
  • Oncological Research: Serves as a precursor for potential prodrugs targeting hormone-related cancers due to its nitrogen mustard functional group.
  • Biochemical Probe: Used in laboratory studies to investigate steroid receptor interactions and signaling pathways.
  • Advanced Medicinal Chemistry: Employed in the design and development of targeted drug delivery systems and cytostatic compounds.
  • Academic & Institutional Research: Utilized in universities and R&D centers for studying structure-activity relationships (SAR) of modified steroids.

Basic Information

Item Detail
Product Name 3-Hydroxy-13,17-Seco-5-Androsten-17-Oic-13,17-Lactam (4-(Bis(2-Chloroethyl)Amino)Phenyl)Butyrate
CAS No. 107480-21-7
Molecular Formula C31H41Cl2N2O4
Molecular Weight 576.58 g/mol
Synonyms 3-Hydroxy-13,17-seco-5-androsten-17-oic-13,17-lactam 4-[bis(2-chloroethyl)amino]phenyl butyrate; 107480-21-7; Seco-Androsten Lactam Nitrogen Mustard Conjugate; Chlorambucil Steroid Ester Derivative; 3-Hydroxy-13,17-secoandrost-5-en-17-oic acid 13,17-lactam 4-[bis(2-chloroethyl)amino]phenyl butanoate
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Quality Control

Our 3-Hydroxy-13,17-Seco-5-Androsten-17-Oic-13,17-Lactam (4-(Bis(2-Chloroethyl)Amino)Phenyl)Butyrate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95.0%
Related Substances (HPLC) Total impurities ≤ 5.0%
Loss on Drying ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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