Description

Methyl 4-Bromo-3-(Trifluoromethyl)Benzoate is a high-value, multi-functional aromatic ester building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for facilitating advanced molecular construction in pharmaceutical and agrochemical research, offering versatile reactivity for cross-coupling and further functionalization. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical intermediate, and advanced material synthesis sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Serves as a critical building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science: Used in the research and development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Research: Employed in academic and industrial laboratories for method development and exploring new synthetic pathways in organic chemistry.
• Fluorine Chemistry: A valuable reagent for introducing fluorine-containing motifs into target molecules, a common strategy to modulate lipophilicity and metabolic stability.

Basic Information

Product Name	Methyl 4-Bromo-3-(Trifluoromethyl)Benzoate
CAS No.	107317-58-8
Molecular Formula	C9H6BrF3O2
Molecular Weight	283.04 g/mol
Synonyms	4-Bromo-3-(trifluoromethyl)benzoic acid methyl ester; Methyl 4-bromo-3-(trifluoromethyl)benzoate; Benzoic acid, 4-bromo-3-(trifluoromethyl)-, methyl ester; Methyl 4-bromo-α,α,α-trifluoro-m-toluate; 4-Bromo-α,α,α-trifluoro-m-toluic acid methyl ester; MFCD03094068
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-3-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.