Description

D-Alloisoleucine, 2-Methyl-, Methyl Ester (9Ci) is a specialized, high-purity chiral building block and ester derivative of the non-proteinogenic amino acid alloisoleucine. This compound matters as a critical intermediate for the synthesis of complex peptides, pharmaceutical actives, and fine chemicals where stereochemical control is paramount. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and advanced organic synthesis sectors for developing novel therapeutic agents and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in metabolic studies, enzyme substrate research, and as a standard for analytical method development.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to introduce the D-alloisoleucine moiety.
• Fine Chemical Production: Employed as a building block for synthesizing complex organic molecules, including natural product analogs and specialty chemicals.
• Catalyst and Ligand Development: Utilized in the preparation of chiral ligands for asymmetric catalysis and organocatalysts.

Basic Information

Product Name	D-Alloisoleucine, 2-Methyl-, Methyl Ester (9Ci)
CAS No.	107246-43-5
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Synonyms	Methyl (2R,3S)-2-amino-3-methylpentanoate; D-2-Amino-3-methylpentanoic acid methyl ester; D-allo-Isoleucine methyl ester; Methyl D-alloisoleucinate; (2R,3S)-2-Amino-3-methylpentanoic acid methyl ester; (R,S)-allo-Isoleucine methyl ester; 2-Methyl-D-alloisoleucine methyl ester
EINECS	Contact for details

Quality Control

Our D-Alloisoleucine, 2-Methyl-, Methyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.