Description

4,5-Dihydrospiro(Furan-3(2H),2'(3'H)-Thieno[2,3-B]Pyridine)-2,3'-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and fused heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting the central nervous system.
• Organic Synthesis Building Block: Used in research and development for constructing novel heterocyclic compounds with potential biological activity.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies in academic and industrial R&D labs.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs).
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	4,5-Dihydrospiro(Furan-3(2H),2'(3'H)-Thieno[2,3-B]Pyridine)-2,3'-Dione
CAS No.	107191-21-9
Molecular Formula	C11H7NO3S
Molecular Weight	233.24 g/mol
Synonyms	4,5-Dihydrospiro[furan-3(2H),2'(3'H)-thieno[2,3-b]pyridine]-2,3'-dione; Spiro[thieno[2,3-b]pyridine-2(3H),3'-furan]-2',3-dione, 4,5-dihydro-; 4,5-Dihydro-2'H-spiro[furan-3,2'-thieno[2,3-b]pyridine]-2,3'-dione; CAS 107191-21-9
EINECS	Contact for details

Quality Control

Our 4,5-Dihydrospiro(Furan-3(2H),2'(3'H)-Thieno[2,3-B]Pyridine)-2,3'-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.