Description

8-Chloro-2,6,6A,7,8,9,10,10A-Octahydro-10-Isocyano-6,6,9-Trimethyl-9-Oxiranylnaphth[1,2,3-Cd]Indole is a complex, polycyclic organic compound featuring a unique indole-derived scaffold with chloro, isocyano, and oxiranyl functional groups. This intricate molecular architecture makes it a valuable and versatile advanced pharmaceutical intermediate for the synthesis of novel active ingredients. It is primarily sought after by research institutions and pharmaceutical R&D departments engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new bioactive molecules.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: The reactive isocyano group allows for its use in creating probes for studying biological pathways and target engagement.
• Academic Research: Utilized in universities and institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	8-Chloro-2,6,6A,7,8,9,10,10A-Octahydro-10-Isocyano-6,6,9-Trimethyl-9-Oxiranylnaphth[1,2,3-Cd]Indole
CAS No.	106865-65-0
Molecular Formula	C20H23ClN2O2
Molecular Weight	358.86 g/mol
Synonyms	8-Chloro-10-isocyano-6,6,9-trimethyl-9-oxiranyl-2,6,6a,7,8,9,10,10a-octahydronaphth[1,2,3-cd]indole; 8-Chloro-10-isocyano-6,6,9-trimethyl-9-oxiranyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinoline; (6aR,9R,10aS)-8-Chloro-10-isocyano-6,6,9-trimethyl-9-oxiranyl-2,3,6a,7,8,9,10,10a-octahydronaphth[1,2,3-cd]indole; 106865-65-0; Benzo[f]quinoline, 8-chloro-1,2,3,4,4a,5,6,10b-octahydro-10-isocyano-6,6,9-trimethyl-9-oxiranyl-; Oxirane, 2-[(6aR,9R,10aS)-8-chloro-10-isocyano-6,6,9-trimethyl-2,3,6a,7,8,9,10,10a-octahydronaphth[1,2,3-cd]indol-9-yl]-
EINECS	Contact for details

Quality Control

Our 8-Chloro-2,6,6A,7,8,9,10,10A-Octahydro-10-Isocyano-6,6,9-Trimethyl-9-Oxiranylnaphth[1,2,3-Cd]Indole is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.