Description

[8R,(-)]-8β-Chloro-9α-Ethenyl-2,6,7,8,9,10-Hexahydro-10α-Isocyano-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole CAS NO 106865-63-8 is a complex, high-purity indole alkaloid derivative characterized by its unique stereochemistry and functional groups. This compound matters as a sophisticated chemical intermediate and research building block for advanced organic synthesis. It is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and specialized fine chemical manufacturers for developing novel active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and anti-cancer research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its complex alkaloid structure for biological activity.
• Chemical Synthesis: Serves as a versatile precursor for creating libraries of complex heterocyclic compounds in medicinal chemistry and drug discovery programs.
• Academic & Institutional Research: Employed in universities and research institutes for studying alkaloid chemistry, reaction mechanisms, and stereoselective synthesis.
• Fine Chemical Production: Acts as a specialty intermediate for manufacturing high-value, low-volume chemicals used in advanced material science.
• Biochemical Probe Development: Utilized in the design and synthesis of molecular probes for investigating biological pathways and protein interactions.

Basic Information

Product Name	[8R,(-)]-8β-Chloro-9α-Ethenyl-2,6,7,8,9,10-Hexahydro-10α-Isocyano-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole
CAS No.	106865-63-8
Molecular Formula	C22H23ClN2
Molecular Weight	350.89 g/mol
Synonyms	(8R)-8-Chloro-9-ethenyl-2,6,7,8,9,10-hexahydro-10-isocyano-6,6,9-trimethylnaphtho[1,2,3-cd]indole; (-)-8β-Chloro-9α-ethenyl-10α-isocyano-6,6,9-trimethyl-2,6,7,8,9,10-hexahydronaphtho[1,2,3-cd]indole; 8β-Chloro-9α-ethenyl-10α-isocyano-6,6,9-trimethyl-2,6,7,8,9,10-hexahydronaphtho[1,2,3-cd]indole; Alkaloid C-22 Indole Derivative; 106865-63-8; (8R)-8-Chloro-9-ethenyl-10-isocyano-6,6,9-trimethyl-2,6,7,8,9,10-hexahydronaphtho[1,2,3-cd]indole
EINECS	Contact for details

Quality Control

Our [8R,(-)]-8β-Chloro-9α-Ethenyl-2,6,7,8,9,10-Hexahydro-10α-Isocyano-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity suitable for research and development. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.