Description

Picropodophyllin-1-Ethyl Ether is a semi-synthetic derivative of podophyllotoxin, a naturally occurring lignan. This compound is valued for its role as a key intermediate in the synthesis of more complex pharmaceutical agents and for its utility in biochemical research. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutic compounds, particularly in the fields of oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential chemotherapeutic and antiviral drugs.
• Biochemical Research: Used as a reference standard or probe in studies investigating tubulin polymerization inhibition and cell cycle arrest.
• Medicinal Chemistry: Serves as a scaffold for the design and development of new chemical entities with targeted biological activity.
• Academic Research: Employed in university and institutional labs for pharmacological and mechanistic studies.

Basic Information

Product Name	Picropodophyllin-1-Ethyl Ether
CAS No.	106709-55-1
Molecular Formula	C24H26O8
Molecular Weight	442.46 g/mol
Synonyms	PPP 1-Ethyl Ether; 1-Ethyl Picropodophyllin Ether; 4'-Demethyl-4-epipodophyllotoxin 1-ethyl ether; 4'-Demethyl-4-epipodophyllotoxin ethyl ether; NSC 367985; 4-Epipodophyllotoxin, 4'-demethyl-, 1-ethyl ether; (5R,5aR,8aR,9R)-9-(Ethoxycarbonyl)-5-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one
EINECS	Contact for details

Quality Control

Our Picropodophyllin-1-Ethyl Ether is produced and tested under strict quality management protocols. We ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere if long-term stability is required.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.