Description

Ethyl 3-(Benzyloxy)Cyclobutanecarboxylate is a high-purity organic building block featuring a cyclobutane ring functionalized with both benzyloxy and ester groups. This compound matters as a versatile and valuable chiral intermediate for the synthesis of complex pharmaceutical molecules and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis.
• Material Science Research: Building block for novel polymers and organic electronic materials due to its rigid cyclobutane core.
• Academic & Contract Research: Essential for method development and synthetic route exploration in university and CRO laboratories.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance and flavor compounds.

Basic Information

Item	Details
Product Name	Ethyl 3-(Benzyloxy)Cyclobutanecarboxylate
CAS No.	106596-81-0
Molecular Formula	C14H18O3
Molecular Weight	234.29 g/mol
Synonyms	3-(Benzyloxy)cyclobutanecarboxylic Acid Ethyl Ester; Ethyl 3-(Phenylmethoxy)cyclobutanecarboxylate; 1-Oxa-2-azaspiro[2.3]hexane-2-carboxylic acid, 6-(phenylmethyl)-, ethyl ester (related); BOC-Protected Cyclobutane Ester Intermediate; Benzyloxy Cyclobutane Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Benzyloxy)Cyclobutanecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.