Description

Ethyl 4-[2-(3,4,5,6-Tetrahydro-2H-Pyridin-1-Yl)Propanoylamino]Benzoate Chloride is a high-purity, advanced pharmaceutical intermediate with a complex molecular structure designed for targeted synthesis. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the controlled synthesis of complex APIs requiring specific piperidine and benzoate functional groups.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Biochemical Research: Employed in the development of enzyme inhibitors or receptor modulators for biochemical assays.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Ethyl 4-[2-(3,4,5,6-Tetrahydro-2H-Pyridin-1-Yl)Propanoylamino]Benzoate Chloride
CAS No.	106572-14-9
Molecular Formula	C17H25ClN2O3
Molecular Weight	340.85 g/mol
Synonyms	Ethyl 4-[[2-(3,4,5,6-Tetrahydro-2H-pyridin-1-yl)propanoyl]amino]benzoate hydrochloride; 4-[[2-(1,2,3,6-Tetrahydro-1-pyridinyl)propanoyl]amino]benzoic Acid Ethyl Ester Hydrochloride; Benzoic acid, 4-[[2-(3,4,5,6-tetrahydro-2H-pyridin-1-yl)propanoyl]amino]-, ethyl ester, hydrochloride; Ethyl 4-(2-(1,2,3,6-tetrahydropyridin-1-yl)propanamido)benzoate hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl 4-[2-(3,4,5,6-Tetrahydro-2H-Pyridin-1-Yl)Propanoylamino]Benzoate Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Ensure the storage area is well-ventilated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.