Description

(2R)-(-)-2-Methylglycidyl 4-Nitrobenzoate is a high-purity chiral epoxide derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its defined stereochemistry and reactive epoxide ring make it invaluable for introducing specific molecular configurations with high enantiomeric purity. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), chiral ligands, and complex specialty molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Chiral Ligand & Catalyst Preparation: Used in the synthesis of enantiomerically pure ligands and organocatalysts for asymmetric catalysis.
• Fine Chemical Synthesis: Employed as a building block for creating complex, high-value specialty chemicals with specific stereocenters.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and stereoselective transformations.
• Agrochemical Intermediate: Potential use in the synthesis of enantiomerically pure agrochemicals and plant growth regulators.

Basic Information

Product Name	(2R)-(-)-2-Methylglycidyl 4-Nitrobenzoate
CAS No.	106268-96-6
Molecular Formula	C11H11NO5
Molecular Weight	237.21 g/mol
Synonyms	(-)-(2R)-2-Methylglycidyl 4-nitrobenzoate; (R)-(-)-2-Methylglycidyl p-nitrobenzoate; (2R)-2-Methyloxiran-2-ylmethyl 4-nitrobenzoate; p-Nitrobenzoic acid (2R)-2-methyloxiran-2-ylmethyl ester; (R)-2-Methylglycidyl 4-nitrobenzoate; Glycidyl 4-nitrobenzoate, 2-methyl-, (2R)-; Chiral 2-methylglycidyl ester
EINECS	Contact for details

Quality Control

Our (2R)-(-)-2-Methylglycidyl 4-Nitrobenzoate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC/Chiral GC), to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, assay, and specific rotation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.